11-Methoxycamptothecin
TL;DR: 11-Methoxycamptothecin (CAS 70906-25-1) is a chemical compound with molecular formula C21H18N2O5 and molecular weight 378.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(19S)-19-ethyl-19-hydroxy-6-methoxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Also Known As: 11-Methoxycamptothecin, (S)-4-ethyl-4-hydroxy-8-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, (19S)-19-ethyl-19-hydroxy-6-methoxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione, (4S)-4alpha-Ethyl-4-hydroxy-8-methoxy-1H-pyrano[3 ,4 :6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
| Molecular Formula | C21H18N2O5 |
|---|---|
| Molecular Weight | 378.12 g/mol |
| LogP | 2.0882 |
| Topological Polar Surface Area | 90.65 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.12158 |
| Heavy Atoms | 28 |
| Complexity | 1229.6736 |
Chemical Identifiers
| CAS Number | 70906-25-1 |
|---|---|
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=C(C=CC5=C4)OC)O |
Product Overview
11-Methoxycamptothecin (CAS 70906-25-1), with molecular formula C21H18N2O5 and molecular weight 378.12 g/mol. IUPAC: (19S)-19-ethyl-19-hydroxy-6-methoxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 11-Methoxycamptothecin
Property Insights of 11-Methoxycamptothecin
The XLogP value of 2.0882 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 11-Methoxycamptothecin. The TPSA of 90.65 Ų falls within the moderate polarity range, balancing permeability and solubility for 11-Methoxycamptothecin. Following Lipinski's Rule of Five, 11-Methoxycamptothecin has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 11-Methoxycamptothecin?
The CAS number of 11-Methoxycamptothecin is 70906-25-1.
What is the molecular formula of 11-Methoxycamptothecin?
The molecular formula of 11-Methoxycamptothecin is C21H18N2O5.
What is the molecular weight of 11-Methoxycamptothecin?
The molecular weight of 11-Methoxycamptothecin is 378.12 g/mol.
Where can I buy 11-Methoxycamptothecin?
You can request a quote for 11-Methoxycamptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 11-Methoxycamptothecin?
Yes, KEHONG BIO provides custom synthesis services for 11-Methoxycamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.