Ketoconazole Impurity 10
TL;DR: Ketoconazole Impurity 10 (CAS 70894-66-5) is a chemical compound with molecular formula C21H18Cl2N2O4 and molecular weight 432.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl benzoate
Also Known As: Ketoconazole Impurity 10, cis-2-2-1,3-dioxolane-4-ylmethylbenzoate, cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol Benzoate (Ester), 2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-ylmethyl benzoate, cis-, cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-ylmethyl benzoate
| Molecular Formula | C21H18Cl2N2O4 |
|---|---|
| Molecular Weight | 432.06 g/mol |
| LogP | 4.3153 |
| Topological Polar Surface Area | 62.58 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 432.06436 |
| Heavy Atoms | 29 |
| Complexity | 981.6109 |
Chemical Identifiers
| CAS Number | 70894-66-5 |
|---|---|
| SMILES | C1[C@@H](O[C@@](O1)(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)COC(=O)C4=CC=CC=C4 |
Product Overview
Ketoconazole Impurity 10 (CAS 70894-66-5), with molecular formula C21H18Cl2N2O4 and molecular weight 432.06 g/mol. IUPAC: [(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl benzoate.
Chemical Property Profile of Ketoconazole Impurity 10
Property Insights of Ketoconazole Impurity 10
The XLogP value of 4.3153 indicates that Ketoconazole Impurity 10 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.58 Ų falls within the moderate polarity range, balancing permeability and solubility for Ketoconazole Impurity 10. Following Lipinski's Rule of Five, Ketoconazole Impurity 10 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ketoconazole Impurity 10?
The CAS number of Ketoconazole Impurity 10 is 70894-66-5.
What is the molecular formula of Ketoconazole Impurity 10?
The molecular formula of Ketoconazole Impurity 10 is C21H18Cl2N2O4.
What is the molecular weight of Ketoconazole Impurity 10?
The molecular weight of Ketoconazole Impurity 10 is 432.06 g/mol.
Where can I buy Ketoconazole Impurity 10?
You can request a quote for Ketoconazole Impurity 10 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ketoconazole Impurity 10?
Yes, KEHONG BIO provides custom synthesis services for Ketoconazole Impurity 10 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.