![2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline structure](/static/products/7084/70842-93-2.webp)
2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline
TL;DR: 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline (CAS 70842-93-2) is a chemical compound with molecular formula C21H23N5O4 and molecular weight 409.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-3-(furan-3-yl)prop-2-en-1-one
Also Known As: 2-(4-(3-(Furan-3-yl)-acryloyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline, 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline, (2E)-1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-3-(furan-3-yl)prop-2-en-1-one, (E)-1-[4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-3-(3-furyl)prop-2-en-1-one, 1-(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)-3-(furan-3-yl)prop-2-en-1-one
| Molecular Formula | C21H23N5O4 |
|---|---|
| Molecular Weight | 409.18 g/mol |
| LogP | 2.1842 |
| Topological Polar Surface Area | 106.95 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 409.17502 |
| Heavy Atoms | 30 |
| Complexity | 1072.6903 |
Chemical Identifiers
| CAS Number | 70842-93-2 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C=CC4=COC=C4)N)OC |
Product Overview
2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline (CAS 70842-93-2), with molecular formula C21H23N5O4 and molecular weight 409.18 g/mol. IUPAC: 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-3-(furan-3-yl)prop-2-en-1-one.
Chemical Property Profile of 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline
Property Insights of 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline
The XLogP value of 2.1842 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline. The TPSA of 106.95 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline. Following Lipinski's Rule of Five, 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline?
The CAS number of 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline is 70842-93-2.
What is the molecular formula of 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline?
The molecular formula of 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline is C21H23N5O4.
What is the molecular weight of 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline?
The molecular weight of 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline is 409.18 g/mol.
Where can I buy 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline?
You can request a quote for 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline?
Yes, KEHONG BIO provides custom synthesis services for 2-{4-[3-(Furan-3-yl)-acryloyl]-piperazin-1-yl}-4-amino-6,7-dimethoxyquinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.