4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one
TL;DR: 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one (CAS 708294-49-9) is a chemical compound with molecular formula C14H8ClFN2O and molecular weight 274.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2-chlorophenyl)-6-fluoro-1H-quinazolin-2-one
Also Known As: BAS 09175679, 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one, 4-(2-chlorophenyl)-6-fluoro-1H-quinazolin-2-one, 4-(2-chlorophenyl)-6-fluoroquinazolin-2(1H)-one, 4-(2-chlorophenyl)-6-fluoro-2(1H)-quinazolinone
| Molecular Formula | C14H8ClFN2O |
|---|---|
| Molecular Weight | 274.03 g/mol |
| LogP | 3.3826 |
| Topological Polar Surface Area | 45.75 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 274.0309 |
| Heavy Atoms | 19 |
| Complexity | 829.03406 |
Chemical Identifiers
| CAS Number | 708294-49-9 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C2=NC(=O)NC3=C2C=C(C=C3)F)Cl |
Product Overview
4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one (CAS 708294-49-9), with molecular formula C14H8ClFN2O and molecular weight 274.03 g/mol. IUPAC: 4-(2-chlorophenyl)-6-fluoro-1H-quinazolin-2-one.
Chemical Property Profile of 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one
Property Insights of 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one
The XLogP value of 3.3826 indicates that 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.75 Ų, 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one?
The CAS number of 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one is 708294-49-9.
What is the molecular formula of 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one?
The molecular formula of 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one is C14H8ClFN2O.
What is the molecular weight of 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one?
The molecular weight of 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one is 274.03 g/mol.
Where can I buy 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one?
You can request a quote for 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(2-Chloro-phenyl)-6-fluoro-1H-quinazolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.