![1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea structure](/static/products/7082/708232-51-3.webp)
1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea
TL;DR: 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea (CAS 708232-51-3) is a chemical compound with molecular formula C18H16FN5O2S2 and molecular weight 417.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea
Also Known As: CBKinase1_007297, CBKinase1_019697, 1-(4-fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea, 4-{[(4-fluoro-2-methylphenyl)carbamothioyl]amino}-N-(pyrimidin-2-yl)benzenesulfonamide, {[4-({[(4-fluoro-2-methylphenyl)amino]thioxomethyl}amino)phenyl]sulfonyl}pyrim idin-2-ylamine
| Molecular Formula | C18H16FN5O2S2 |
|---|---|
| Molecular Weight | 417.07 g/mol |
| LogP | 3.53382 |
| Topological Polar Surface Area | 96.01 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 417.07294 |
| Heavy Atoms | 28 |
| Complexity | 1090.7186 |
Chemical Identifiers
| CAS Number | 708232-51-3 |
|---|---|
| SMILES | CC1=C(C=CC(=C1)F)NC(=S)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC=CC=N3 |
Product Overview
1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea (CAS 708232-51-3), with molecular formula C18H16FN5O2S2 and molecular weight 417.07 g/mol. IUPAC: 1-(4-fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea.
Chemical Property Profile of 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea
Property Insights of 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea
The XLogP value of 3.53382 indicates that 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 96.01 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea. Following Lipinski's Rule of Five, 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea?
The CAS number of 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea is 708232-51-3.
What is the molecular formula of 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea?
The molecular formula of 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea is C18H16FN5O2S2.
What is the molecular weight of 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea?
The molecular weight of 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea is 417.07 g/mol.
Where can I buy 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea?
You can request a quote for 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-Fluoro-2-methylphenyl)-3-[4-(pyrimidin-2-ylsulfamoyl)phenyl]thiourea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.