Flutroline
TL;DR: Flutroline (CAS 70801-02-4) is a chemical compound with molecular formula C27H25F3N2O and molecular weight 450.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[8-fluoro-5-(4-fluorophenyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]-1-(4-fluorophenyl)butan-1-ol
Also Known As: Flutrolinum, Flutrolina, Flutrolino, Flutroline [USAN:INN], Flutrolinum [INN-Latin]
| Molecular Formula | C27H25F3N2O |
|---|---|
| Molecular Weight | 450.19 g/mol |
| LogP | 5.4 |
| Topological Polar Surface Area | 28.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 450.1919 |
| Heavy Atoms | 33 |
| Complexity | 622.0 |
Chemical Identifiers
| CAS Number | 70801-02-4 |
|---|---|
| SMILES | C1CN(CC2=C1N(C3=C2C=C(C=C3)F)C4=CC=C(C=C4)F)CCCC(C5=CC=C(C=C5)F)O |
| InChIKey | OYGDOCFZQVGFIP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Flutroline (CAS 70801-02-4), with molecular formula C27H25F3N2O and molecular weight 450.19 g/mol. IUPAC: 4-[8-fluoro-5-(4-fluorophenyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]-1-(4-fluorophenyl)butan-1-ol.
Chemical Property Profile of Flutroline
Property Insights of Flutroline
The XLogP value of 5.4 indicates that Flutroline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.4 Ų, Flutroline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Flutroline has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Flutroline?
The CAS number of Flutroline is 70801-02-4.
What is the molecular formula of Flutroline?
The molecular formula of Flutroline is C27H25F3N2O.
What is the molecular weight of Flutroline?
The molecular weight of Flutroline is 450.19 g/mol.
Where can I buy Flutroline?
You can request a quote for Flutroline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Flutroline?
Yes, KEHONG BIO provides custom synthesis services for Flutroline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.