![1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione structure](/static/products/7067/7067-24-5.webp)
1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione
TL;DR: 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione (CAS 7067-24-5) is a chemical compound with molecular formula C25H19FN4O4S and molecular weight 490.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione
Also Known As: 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione, 1-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione
| Molecular Formula | C25H19FN4O4S |
|---|---|
| Molecular Weight | 490.11 g/mol |
| LogP | 4.37564 |
| Topological Polar Surface Area | 104.87 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 490.1111 |
| Heavy Atoms | 35 |
| Complexity | 1568.0844 |
Chemical Identifiers
| CAS Number | 7067-24-5 |
|---|---|
| SMILES | CC1=C(N2C=CC=CC2=N1)C(=C3C(N(C(=O)C3=O)C4=NC(=C(S4)C(=O)C)C)C5=CC=C(C=C5)F)O |
Product Overview
1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione (CAS 7067-24-5), with molecular formula C25H19FN4O4S and molecular weight 490.11 g/mol. IUPAC: 1-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione.
Chemical Property Profile of 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione
Property Insights of 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione
The XLogP value of 4.37564 indicates that 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 104.87 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione. Following Lipinski's Rule of Five, 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione?
The CAS number of 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione is 7067-24-5.
What is the molecular formula of 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione?
The molecular formula of 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione is C25H19FN4O4S.
What is the molecular weight of 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione?
The molecular weight of 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione is 490.11 g/mol.
Where can I buy 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione?
You can request a quote for 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for 1-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-fluorophenyl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.