Dansylsulfonamido-bleomycin A2 structure

Dansylsulfonamido-bleomycin A2

TL;DR: Dansylsulfonamido-bleomycin A2 (CAS 70577-43-4) is a chemical compound with molecular formula C67H95N18O23S4+ and molecular weight 1647.57 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[[5-[2-[2-[[2-[[4-[[2-[[6-amino-2-[3-amino-1-[[3-amino-2-[[6-(dimethylamino)naphthalen-1-yl]sulfonylamino]-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium

Also Known As: Dihydroxyboryldeoxyuridine, Dansylsulfonamido-bleomycin A2, N38-((5-(Dimethylamino)-1-naphthalenyl)sulfonyl)-N1-(3-(dimethylsulfonio)propyl)bleomycinamide, 3-[[5-[2-[2-[[2-[[4-[[2-[[6-amino-2-[3-amino-1-[[3-amino-2-[[6-(dimethylamino)naphthalen-1-yl]sulfonylamino]-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium, Bleomycinamide, N38-((5-(dimethylamino)-1-naphthalenyl)sulfonyl)-N1-(3-(dimethylsulfonio)propyl)-

CAS: 70577-43-4
Molecular Formula C67H95N18O23S4+
Molecular Weight 1647.57 g/mol
LogP -4.5
Topological Polar Surface Area 716.0 Ų
Hydrogen Bond Donors 20
Hydrogen Bond Acceptors 34
Rotatable Bonds 40
Exact Mass 1647.5701
Heavy Atoms 112
Complexity 3230.0

Chemical Identifiers

CAS Number 70577-43-4
SMILES CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)NS(=O)(=O)C2=CC=CC3=C2C=CC(=C3)N(C)C)C(=O)NC(C(C4=CN=CN4)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC7=NC(=CS7)C8=C(N=CS8)C(=O)NCCC[S+](C)C)O
InChIKey MXONIQQSRZTMNM-UHFFFAOYSA-O

Product Overview

Dansylsulfonamido-bleomycin A2 (CAS 70577-43-4), with molecular formula C67H95N18O23S4+ and molecular weight 1647.57 g/mol. IUPAC: 3-[[5-[2-[2-[[2-[[4-[[2-[[6-amino-2-[3-amino-1-[[3-amino-2-[[6-(dimethylamino)naphthalen-1-yl]sulfonylamino]-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Dansylsulfonamido-bleomycin A2

XLogP
-4.5
TPSA (Topological Polar Surface Area)
716.0
Hydrogen Bond Donors
20
Hydrogen Bond Acceptors
34
Rotatable Bonds
40
Heavy Atoms
112
Complexity
3230.0
Exact Mass
1647.5701
Monoisotopic Mass
1647.5701
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Dansylsulfonamido-bleomycin A2

The XLogP value of -4.5 indicates that Dansylsulfonamido-bleomycin A2 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 716.0 Ų indicates high polarity, suggesting Dansylsulfonamido-bleomycin A2 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Dansylsulfonamido-bleomycin A2 has 20 hydrogen bond donor(s) and 34 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Dansylsulfonamido-bleomycin A2?

The CAS number of Dansylsulfonamido-bleomycin A2 is 70577-43-4.

What is the molecular formula of Dansylsulfonamido-bleomycin A2?

The molecular formula of Dansylsulfonamido-bleomycin A2 is C67H95N18O23S4+.

What is the molecular weight of Dansylsulfonamido-bleomycin A2?

The molecular weight of Dansylsulfonamido-bleomycin A2 is 1647.57 g/mol.

Where can I buy Dansylsulfonamido-bleomycin A2?

You can request a quote for Dansylsulfonamido-bleomycin A2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Dansylsulfonamido-bleomycin A2?

Yes, KEHONG BIO provides custom synthesis services for Dansylsulfonamido-bleomycin A2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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