Trifluridine
TL;DR: Trifluridine (CAS 7057-42-3) is a chemical compound with molecular formula C10H11F3N2O5 and molecular weight 296.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione
Also Known As: Trifluridine, 5-Trifluorothymidine, Viroptic, TRIFLUOROTHYMIDINE, F3DThd
| Molecular Formula | C10H11F3N2O5 |
|---|---|
| Molecular Weight | 296.06 g/mol |
| LogP | -0.5 |
| Topological Polar Surface Area | 99.1 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 296.062 |
| Heavy Atoms | 20 |
| Complexity | 464.0 |
Chemical Identifiers
| CAS Number | 7057-42-3 |
|---|---|
| SMILES | C1C(C(OC1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O |
| InChIKey | VSQQQLOSPVPRAZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Trifluridine (CAS 7057-42-3), with molecular formula C10H11F3N2O5 and molecular weight 296.06 g/mol. IUPAC: 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione.
Chemical Property Profile of Trifluridine
Property Insights of Trifluridine
The XLogP value of -0.5 indicates that Trifluridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Trifluridine. Following Lipinski's Rule of Five, Trifluridine has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Trifluridine?
The CAS number of Trifluridine is 7057-42-3.
What is the molecular formula of Trifluridine?
The molecular formula of Trifluridine is C10H11F3N2O5.
What is the molecular weight of Trifluridine?
The molecular weight of Trifluridine is 296.06 g/mol.
Where can I buy Trifluridine?
You can request a quote for Trifluridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Trifluridine?
Yes, KEHONG BIO provides custom synthesis services for Trifluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.