3-(Trifluoromethyl)benzyl chloride structure

3-(Trifluoromethyl)benzyl chloride

TL;DR: 3-(Trifluoromethyl)benzyl chloride (CAS 705-29-3) is a chemical compound with molecular formula C8H6ClF3 and molecular weight 194.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(chloromethyl)-3-(trifluoromethyl)benzene

Also Known As: 3-(Trifluoromethyl)benzyl chloride, 1-(Chloromethyl)-3-(trifluoromethyl)benzene, 3-Trifluoromethylbenzyl chloride, g1r cxfff, 3-(Chloromethyl)benzotrifluoride

CAS: 705-29-3
Molecular Formula C8H6ClF3
Molecular Weight 194.01 g/mol
LogP 3.5
Topological Polar Surface Area 0.0 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 1
Exact Mass 194.01102
Heavy Atoms 12
Complexity 144.0

Chemical Identifiers

CAS Number 705-29-3
SMILES C1=CC(=CC(=C1)C(F)(F)F)CCl
InChIKey XGASTRVQNVVYIZ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (59 patents) Dyes & Pigments (1 patents) Heterocyclic Building Blocks (560 patents) Organic Building Blocks (283 patents) Organometallic Reagents (9 patents) +6 more

Product Overview

3-(Trifluoromethyl)benzyl chloride (CAS 705-29-3), with molecular formula C8H6ClF3 and molecular weight 194.01 g/mol. IUPAC: 1-(chloromethyl)-3-(trifluoromethyl)benzene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 3-(Trifluoromethyl)benzyl chloride

XLogP
3.5
TPSA (Topological Polar Surface Area)
0.0
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
1
Heavy Atoms
12
Complexity
144.0
Exact Mass
194.01102
Monoisotopic Mass
194.01102
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-(Trifluoromethyl)benzyl chloride

The XLogP value of 3.5 indicates that 3-(Trifluoromethyl)benzyl chloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 0.0 Ų, 3-(Trifluoromethyl)benzyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(Trifluoromethyl)benzyl chloride has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-(Trifluoromethyl)benzyl chloride?

The CAS number of 3-(Trifluoromethyl)benzyl chloride is 705-29-3.

What is the molecular formula of 3-(Trifluoromethyl)benzyl chloride?

The molecular formula of 3-(Trifluoromethyl)benzyl chloride is C8H6ClF3.

What is the molecular weight of 3-(Trifluoromethyl)benzyl chloride?

The molecular weight of 3-(Trifluoromethyl)benzyl chloride is 194.01 g/mol.

Where can I buy 3-(Trifluoromethyl)benzyl chloride?

You can request a quote for 3-(Trifluoromethyl)benzyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-(Trifluoromethyl)benzyl chloride?

Yes, KEHONG BIO provides custom synthesis services for 3-(Trifluoromethyl)benzyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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