![4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one structure](/static/products/7049/7049-03-8.webp)
4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one
TL;DR: 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one (CAS 7049-03-8) is a chemical compound with molecular formula C25H23N3O4S and molecular weight 461.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-2-(3-prop-2-enoxyphenyl)-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one
Also Known As: 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one, 3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-2-(3-prop-2-enoxyphenyl)-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one
| Molecular Formula | C25H23N3O4S |
|---|---|
| Molecular Weight | 461.14 g/mol |
| LogP | 4.49824 |
| Topological Polar Surface Area | 92.62 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 461.14093 |
| Heavy Atoms | 33 |
| Complexity | 1249.5477 |
Chemical Identifiers
| CAS Number | 7049-03-8 |
|---|---|
| SMILES | CC1=C(SC(=N1)C)C(=O)C2=C(C(=O)N(C2C3=CC(=CC=C3)OCC=C)CC4=CN=CC=C4)O |
Product Overview
4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one (CAS 7049-03-8), with molecular formula C25H23N3O4S and molecular weight 461.14 g/mol. IUPAC: 3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-2-(3-prop-2-enoxyphenyl)-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one.
Chemical Property Profile of 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one
Property Insights of 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one
The XLogP value of 4.49824 indicates that 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 92.62 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one. Following Lipinski's Rule of Five, 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one?
The CAS number of 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one is 7049-03-8.
What is the molecular formula of 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one?
The molecular formula of 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one is C25H23N3O4S.
What is the molecular weight of 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one?
The molecular weight of 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one is 461.14 g/mol.
Where can I buy 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one?
You can request a quote for 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(2,4-Dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{3-[(prop-2-en-1-yl)oxy]phenyl}-1-[(pyridin-3-yl)methyl]-1,5-dihydro-2H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.