![1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one structure](/static/products/7049/7049-02-7.webp)
1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one
TL;DR: 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one (CAS 7049-02-7) is a chemical compound with molecular formula C24H29N3O4S and molecular weight 455.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3-(dimethylamino)propyl]-3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-2-(4-prop-2-enoxyphenyl)-2H-pyrrol-5-one
Also Known As: 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one, 1-[3-(dimethylamino)propyl]-3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-2-(4-prop-2-enoxyphenyl)-2H-pyrrol-5-one
| Molecular Formula | C24H29N3O4S |
|---|---|
| Molecular Weight | 455.19 g/mol |
| LogP | 3.85474 |
| Topological Polar Surface Area | 82.97 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 10 |
| Exact Mass | 455.18787 |
| Heavy Atoms | 32 |
| Complexity | 1040.0138 |
Chemical Identifiers
| CAS Number | 7049-02-7 |
|---|---|
| SMILES | CC1=C(SC(=N1)C)C(=O)C2=C(C(=O)N(C2C3=CC=C(C=C3)OCC=C)CCCN(C)C)O |
Product Overview
1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one (CAS 7049-02-7), with molecular formula C24H29N3O4S and molecular weight 455.19 g/mol. IUPAC: 1-[3-(dimethylamino)propyl]-3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-2-(4-prop-2-enoxyphenyl)-2H-pyrrol-5-one.
Chemical Property Profile of 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one
Property Insights of 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one
The XLogP value of 3.85474 indicates that 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 82.97 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one. Following Lipinski's Rule of Five, 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one?
The CAS number of 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one is 7049-02-7.
What is the molecular formula of 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one?
The molecular formula of 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one is C24H29N3O4S.
What is the molecular weight of 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one?
The molecular weight of 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one is 455.19 g/mol.
Where can I buy 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one?
You can request a quote for 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 1-[3-(Dimethylamino)propyl]-4-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-hydroxy-5-{4-[(prop-2-en-1-yl)oxy]phenyl}-1,5-dihydro-2H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.