![1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one structure](/static/products/7048/7048-85-3.webp)
1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one
TL;DR: 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 7048-85-3) is a chemical compound with molecular formula C27H29N3O4S and molecular weight 491.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(dimethylamino)ethyl]-2-(4-ethoxyphenyl)-4-hydroxy-3-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-2H-pyrrol-5-one
Also Known As: 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one, 1-(2-dimethylaminoethyl)-2-(4-ethoxyphenyl)-4-hydroxy-3-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-2H-pyrrol-5-one
| Molecular Formula | C27H29N3O4S |
|---|---|
| Molecular Weight | 491.19 g/mol |
| LogP | 4.65712 |
| Topological Polar Surface Area | 82.97 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 9 |
| Exact Mass | 491.18787 |
| Heavy Atoms | 35 |
| Complexity | 1249.1906 |
Chemical Identifiers
| CAS Number | 7048-85-3 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)C2C(=C(C(=O)N2CCN(C)C)O)C(=O)C3=C(N=C(S3)C4=CC=CC=C4)C |
Product Overview
1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 7048-85-3), with molecular formula C27H29N3O4S and molecular weight 491.19 g/mol. IUPAC: 1-[2-(dimethylamino)ethyl]-2-(4-ethoxyphenyl)-4-hydroxy-3-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-2H-pyrrol-5-one.
Chemical Property Profile of 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one
Property Insights of 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one
The XLogP value of 4.65712 indicates that 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 82.97 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one. Following Lipinski's Rule of Five, 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
The CAS number of 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one is 7048-85-3.
What is the molecular formula of 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
The molecular formula of 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one is C27H29N3O4S.
What is the molecular weight of 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
The molecular weight of 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one is 491.19 g/mol.
Where can I buy 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
You can request a quote for 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 1-[2-(Dimethylamino)ethyl]-5-(4-ethoxyphenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.