![1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one structure](/static/products/7048/7048-84-2.webp)
1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one
TL;DR: 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 7048-84-2) is a chemical compound with molecular formula C25H24FN3O3S and molecular weight 465.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(dimethylamino)ethyl]-2-(4-fluorophenyl)-4-hydroxy-3-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-2H-pyrrol-5-one
Also Known As: 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one, 1-(2-dimethylaminoethyl)-2-(4-fluorophenyl)-4-hydroxy-3-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-2H-pyrrol-5-one
| Molecular Formula | C25H24FN3O3S |
|---|---|
| Molecular Weight | 465.15 g/mol |
| LogP | 4.39752 |
| Topological Polar Surface Area | 73.74 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 465.15225 |
| Heavy Atoms | 33 |
| Complexity | 1219.454 |
Chemical Identifiers
| CAS Number | 7048-84-2 |
|---|---|
| SMILES | CC1=C(SC(=N1)C2=CC=CC=C2)C(=O)C3=C(C(=O)N(C3C4=CC=C(C=C4)F)CCN(C)C)O |
Product Overview
1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 7048-84-2), with molecular formula C25H24FN3O3S and molecular weight 465.15 g/mol. IUPAC: 1-[2-(dimethylamino)ethyl]-2-(4-fluorophenyl)-4-hydroxy-3-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-2H-pyrrol-5-one.
Chemical Property Profile of 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one
Property Insights of 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one
The XLogP value of 4.39752 indicates that 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.74 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one. Following Lipinski's Rule of Five, 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
The CAS number of 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one is 7048-84-2.
What is the molecular formula of 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
The molecular formula of 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one is C25H24FN3O3S.
What is the molecular weight of 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
The molecular weight of 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one is 465.15 g/mol.
Where can I buy 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
You can request a quote for 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 1-[2-(Dimethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1,5-dihydro-2H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.