Dehydroftorafur
TL;DR: Dehydroftorafur (CAS 70460-49-0) is a chemical compound with molecular formula C8H7FN2O3 and molecular weight 198.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(2,3-dihydrofuran-2-yl)-5-fluoropyrimidine-2,4-dione
Also Known As: Dehydroftorafur, 2,4(1H,3H)-Pyrimidinedione, 1-(2,3-dihydro-2-furanyl)-5-fluoro-, 1-(2,3-Dihydro-2-furanyl)-5-fluorouracil, 1-(2,3-Dihydrofuran-2-yl)-5-fluorouracil, 1-(2,3-Dihydro-2-furanyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione
| Molecular Formula | C8H7FN2O3 |
|---|---|
| Molecular Weight | 198.04 g/mol |
| LogP | 0.3 |
| Topological Polar Surface Area | 58.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 198.04407 |
| Heavy Atoms | 14 |
| Complexity | 350.0 |
Chemical Identifiers
| CAS Number | 70460-49-0 |
|---|---|
| SMILES | C1C=COC1N2C=C(C(=O)NC2=O)F |
| InChIKey | PDLPZZHYCMXDCF-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Dehydroftorafur (CAS 70460-49-0), with molecular formula C8H7FN2O3 and molecular weight 198.04 g/mol. IUPAC: 1-(2,3-dihydrofuran-2-yl)-5-fluoropyrimidine-2,4-dione.
Chemical Property Profile of Dehydroftorafur
Property Insights of Dehydroftorafur
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dehydroftorafur. With a topological polar surface area (TPSA) of 58.6 Ų, Dehydroftorafur exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dehydroftorafur has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Dehydroftorafur?
The CAS number of Dehydroftorafur is 70460-49-0.
What is the molecular formula of Dehydroftorafur?
The molecular formula of Dehydroftorafur is C8H7FN2O3.
What is the molecular weight of Dehydroftorafur?
The molecular weight of Dehydroftorafur is 198.04 g/mol.
Where can I buy Dehydroftorafur?
You can request a quote for Dehydroftorafur directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Dehydroftorafur?
Yes, KEHONG BIO provides custom synthesis services for Dehydroftorafur and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.