N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide
TL;DR: N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide (CAS 701973-20-8) is a chemical compound with molecular formula C18H18ClFN2OS and molecular weight 364.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide
Also Known As: N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide, N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydroquinoline-1(2H)-carbothioamide, [(5-chloro-2-methoxyphenyl)amino](6-fluoro-2-methyl(1,2,3,4-tetrahydroquinolyl ))methane-1-thione
| Molecular Formula | C18H18ClFN2OS |
|---|---|
| Molecular Weight | 364.08 g/mol |
| LogP | 5.0258 |
| Topological Polar Surface Area | 24.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 364.08124 |
| Heavy Atoms | 24 |
| Complexity | 783.60925 |
Chemical Identifiers
| CAS Number | 701973-20-8 |
|---|---|
| SMILES | CC1CCC2=C(N1C(=S)NC3=C(C=CC(=C3)Cl)OC)C=CC(=C2)F |
Product Overview
N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide (CAS 701973-20-8), with molecular formula C18H18ClFN2OS and molecular weight 364.08 g/mol. IUPAC: N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide.
Chemical Property Profile of N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide
Property Insights of N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide
The XLogP value of 5.0258 indicates that N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 24.5 Ų, N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide?
The CAS number of N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide is 701973-20-8.
What is the molecular formula of N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide?
The molecular formula of N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide is C18H18ClFN2OS.
What is the molecular weight of N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide?
The molecular weight of N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide is 364.08 g/mol.
Where can I buy N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide?
You can request a quote for N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-chloro-2-methoxyphenyl)-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothioamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.