Lofemizole hydrochloride
TL;DR: Lofemizole hydrochloride (CAS 70169-80-1) is a chemical compound with molecular formula C10H10Cl2N2 and molecular weight 228.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-chlorophenyl)-5-methyl-1H-imidazole;hydrochloride
Also Known As: Lofemizole hydrochloride, Lofemizole HCl, lofemizolehydrochloride, Lofemizole hydrochloride [USAN], 4-(4-Chlorophenyl)-5-methyl-1H-imidazole hydrochloride
| Molecular Formula | C10H10Cl2N2 |
|---|---|
| Molecular Weight | 228.02 g/mol |
| LogP | 3.46 |
| Topological Polar Surface Area | 28.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 228.02211 |
| Heavy Atoms | 14 |
| Complexity | 166.0 |
Chemical Identifiers
| CAS Number | 70169-80-1 |
|---|---|
| SMILES | CC1=C(N=CN1)C2=CC=C(C=C2)Cl.Cl |
| InChIKey | PIAMNHTVFPWVHG-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lofemizole hydrochloride (CAS 70169-80-1), with molecular formula C10H10Cl2N2 and molecular weight 228.02 g/mol. IUPAC: 4-(4-chlorophenyl)-5-methyl-1H-imidazole;hydrochloride.
Chemical Property Profile of Lofemizole hydrochloride
Property Insights of Lofemizole hydrochloride
The XLogP value of 3.46 indicates that Lofemizole hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.7 Ų, Lofemizole hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lofemizole hydrochloride has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lofemizole hydrochloride?
The CAS number of Lofemizole hydrochloride is 70169-80-1.
What is the molecular formula of Lofemizole hydrochloride?
The molecular formula of Lofemizole hydrochloride is C10H10Cl2N2.
What is the molecular weight of Lofemizole hydrochloride?
The molecular weight of Lofemizole hydrochloride is 228.02 g/mol.
Where can I buy Lofemizole hydrochloride?
You can request a quote for Lofemizole hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lofemizole hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Lofemizole hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.