DGAT-1 inhibitor
TL;DR: DGAT-1 inhibitor (CAS 701236-77-3) is a chemical compound with molecular formula C22H26N4O3 and molecular weight 394.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[4-(4-amino-7,7-dimethylpyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl]acetic acid
Also Known As: DGAT-1 inhibitor, T863 (DGAT-3), trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid, DGAT-1 inhibitor;T 863;T-863, cis-4-[4- phenyl]cyclohexaneaceticacid
| Molecular Formula | C22H26N4O3 |
|---|---|
| Molecular Weight | 394.20 g/mol |
| LogP | 4.0991 |
| Topological Polar Surface Area | 110.69 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 394.2005 |
| Heavy Atoms | 29 |
| Complexity | 945.0298 |
Chemical Identifiers
| CAS Number | 701236-77-3 |
|---|---|
| SMILES | CC1(C(=NC2=C(N=CN=C2O1)N)C3=CC=C(C=C3)C4CCC(CC4)CC(=O)O)C |
Product Overview
DGAT-1 inhibitor (CAS 701236-77-3), with molecular formula C22H26N4O3 and molecular weight 394.20 g/mol. IUPAC: 2-[4-[4-(4-amino-7,7-dimethylpyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl]acetic acid.
Chemical Property Profile of DGAT-1 inhibitor
Property Insights of DGAT-1 inhibitor
The XLogP value of 4.0991 indicates that DGAT-1 inhibitor is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.69 Ų falls within the moderate polarity range, balancing permeability and solubility for DGAT-1 inhibitor. Following Lipinski's Rule of Five, DGAT-1 inhibitor has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of DGAT-1 inhibitor?
The CAS number of DGAT-1 inhibitor is 701236-77-3.
What is the molecular formula of DGAT-1 inhibitor?
The molecular formula of DGAT-1 inhibitor is C22H26N4O3.
What is the molecular weight of DGAT-1 inhibitor?
The molecular weight of DGAT-1 inhibitor is 394.20 g/mol.
Where can I buy DGAT-1 inhibitor?
You can request a quote for DGAT-1 inhibitor directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for DGAT-1 inhibitor?
Yes, KEHONG BIO provides custom synthesis services for DGAT-1 inhibitor and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.