Colchicine, 10-demethoxy-10-(diethylamino)-
TL;DR: Colchicine, 10-demethoxy-10-(diethylamino)- (CAS 6962-03-4) is a chemical compound with molecular formula C25H32N2O5 and molecular weight 440.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-10-(diethylamino)-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: 10-Demethoxy-10-(diethylamino)colchicine, COLCHICINE, 10-DEMETHOXY-10-(DIETHYLAMINO)-, 4-14-00-00924 (Beilstein Handbook Reference), Benzo[a]heptalen-9(5H)-one,7-dihydro-1,2,3-trimethoxy-, N-[(7S)-10-(diethylamino)-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
| Molecular Formula | C25H32N2O5 |
|---|---|
| Molecular Weight | 440.23 g/mol |
| LogP | 2.4 |
| Topological Polar Surface Area | 77.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 440.2311 |
| Heavy Atoms | 32 |
| Complexity | 798.0 |
Chemical Identifiers
| CAS Number | 6962-03-4 |
|---|---|
| SMILES | CCN(CC)C1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)C |
| InChIKey | VBJDWXFOMWSFLB-IBGZPJMESA-N |
Product Overview
Colchicine, 10-demethoxy-10-(diethylamino)- (CAS 6962-03-4), with molecular formula C25H32N2O5 and molecular weight 440.23 g/mol. IUPAC: N-[(7S)-10-(diethylamino)-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of Colchicine, 10-demethoxy-10-(diethylamino)-
Property Insights of Colchicine, 10-demethoxy-10-(diethylamino)-
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Colchicine, 10-demethoxy-10-(diethylamino)-. The TPSA of 77.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Colchicine, 10-demethoxy-10-(diethylamino)-. Following Lipinski's Rule of Five, Colchicine, 10-demethoxy-10-(diethylamino)- has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicine, 10-demethoxy-10-(diethylamino)-?
The CAS number of Colchicine, 10-demethoxy-10-(diethylamino)- is 6962-03-4.
What is the molecular formula of Colchicine, 10-demethoxy-10-(diethylamino)-?
The molecular formula of Colchicine, 10-demethoxy-10-(diethylamino)- is C25H32N2O5.
What is the molecular weight of Colchicine, 10-demethoxy-10-(diethylamino)-?
The molecular weight of Colchicine, 10-demethoxy-10-(diethylamino)- is 440.23 g/mol.
Where can I buy Colchicine, 10-demethoxy-10-(diethylamino)-?
You can request a quote for Colchicine, 10-demethoxy-10-(diethylamino)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicine, 10-demethoxy-10-(diethylamino)-?
Yes, KEHONG BIO provides custom synthesis services for Colchicine, 10-demethoxy-10-(diethylamino)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.