4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid structure

4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid

TL;DR: 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid (CAS 6954-64-9) is a chemical compound with molecular formula C10H7F2NO3 and molecular weight 227.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(2,4-difluoroanilino)-4-oxobut-2-enoic acid

Also Known As: NCIOpen2_003219, 4-(2,4-difluoroanilino)-4-oxobut-2-enoic acid, N-(2,4-Difluorophenyl)maleamic acid, 3-[(2,4-difluorophenyl)carbamoyl]prop-2-enoic acid, 3-(n-(2,4-difluorophenyl)carbamoyl)prop-2-enoic acid

CAS: 6954-64-9
Molecular Formula C10H7F2NO3
Molecular Weight 227.04 g/mol
LogP 1.1
Topological Polar Surface Area 66.4 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 3
Exact Mass 227.0394
Heavy Atoms 16
Complexity 306.0

Chemical Identifiers

CAS Number 6954-64-9
SMILES C1=CC(=C(C=C1F)F)NC(=O)C=CC(=O)O
InChIKey DVBSHLGHHLTWPZ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (7 patents) Pharmaceutical Intermediates (8 patents)

Product Overview

4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid (CAS 6954-64-9), with molecular formula C10H7F2NO3 and molecular weight 227.04 g/mol. IUPAC: 4-(2,4-difluoroanilino)-4-oxobut-2-enoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid

XLogP
1.1
TPSA (Topological Polar Surface Area)
66.4
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
3
Heavy Atoms
16
Complexity
306.0
Exact Mass
227.0394
Monoisotopic Mass
227.0394
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid

The XLogP value of 1.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid. The TPSA of 66.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid. Following Lipinski's Rule of Five, 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid?

The CAS number of 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid is 6954-64-9.

What is the molecular formula of 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid?

The molecular formula of 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid is C10H7F2NO3.

What is the molecular weight of 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid?

The molecular weight of 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid is 227.04 g/mol.

Where can I buy 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid?

You can request a quote for 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid?

Yes, KEHONG BIO provides custom synthesis services for 4-((2,4-Difluorophenyl)amino)-4-oxo-2-butenoic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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