1H-Benzimidazole-6-carbonitrile structure

1H-Benzimidazole-6-carbonitrile

TL;DR: 1H-Benzimidazole-6-carbonitrile (CAS 6948-72-7) is a chemical compound with molecular formula C8H5N3 and molecular weight 143.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3H-benzimidazole-5-carbonitrile

Also Known As: 1H-Benzimidazole-5-carbonitrile, 5-Cyanobenzimidazole, 1H-BENZO[D]IMIDAZOLE-6-CARBONITRILE, null, 1H-Benzimidazole-6-carbonitrile

CAS: 6948-72-7
Molecular Formula C8H5N3
Molecular Weight 143.05 g/mol
LogP 1.5
Topological Polar Surface Area 52.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 0
Exact Mass 143.04834
Heavy Atoms 11
Complexity 193.0

Chemical Identifiers

CAS Number 6948-72-7
SMILES C1=CC2=C(C=C1C#N)NC=N2
InChIKey NICYTXJGZRYCEQ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (5 patents) Analytical Reagents (1 patents) Heterocyclic Building Blocks (116 patents) Organic Building Blocks (11 patents) Pharmaceutical Intermediates (87 patents) +1 more

Product Overview

1H-Benzimidazole-6-carbonitrile (CAS 6948-72-7), with molecular formula C8H5N3 and molecular weight 143.05 g/mol. IUPAC: 3H-benzimidazole-5-carbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 1H-Benzimidazole-6-carbonitrile

XLogP
1.5
TPSA (Topological Polar Surface Area)
52.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
11
Complexity
193.0
Exact Mass
143.04834
Monoisotopic Mass
143.04834
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1H-Benzimidazole-6-carbonitrile

The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1H-Benzimidazole-6-carbonitrile. With a topological polar surface area (TPSA) of 52.5 Ų, 1H-Benzimidazole-6-carbonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1H-Benzimidazole-6-carbonitrile has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1H-Benzimidazole-6-carbonitrile?

The CAS number of 1H-Benzimidazole-6-carbonitrile is 6948-72-7.

What is the molecular formula of 1H-Benzimidazole-6-carbonitrile?

The molecular formula of 1H-Benzimidazole-6-carbonitrile is C8H5N3.

What is the molecular weight of 1H-Benzimidazole-6-carbonitrile?

The molecular weight of 1H-Benzimidazole-6-carbonitrile is 143.05 g/mol.

Where can I buy 1H-Benzimidazole-6-carbonitrile?

You can request a quote for 1H-Benzimidazole-6-carbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1H-Benzimidazole-6-carbonitrile?

Yes, KEHONG BIO provides custom synthesis services for 1H-Benzimidazole-6-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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