![1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine structure](/static/products/6944/694475-26-8.webp)
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine
TL;DR: 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine (CAS 694475-26-8) is a chemical compound with molecular formula C8H10F3N3S and molecular weight 237.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-piperidin-1-yl-5-(trifluoromethyl)-1,3,4-thiadiazole
Also Known As: 1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine, 2-piperidino-5-trifluoromethyl-1,3,4-thiadiazole, 2-piperidin-1-yl-5-(trifluoromethyl)-1,3,4-thiadiazole, 2-(piperidin-1-yl)-5-(trifluoromethyl)-1,3,4-thiadiazole
| Molecular Formula | C8H10F3N3S |
|---|---|
| Molecular Weight | 237.05 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 57.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 237.05475 |
| Heavy Atoms | 15 |
| Complexity | 218.0 |
Chemical Identifiers
| CAS Number | 694475-26-8 |
|---|---|
| SMILES | C1CCN(CC1)C2=NN=C(S2)C(F)(F)F |
| InChIKey | MIZAXPVYVZIIRW-UHFFFAOYSA-N |
Product Overview
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine (CAS 694475-26-8), with molecular formula C8H10F3N3S and molecular weight 237.05 g/mol. IUPAC: 2-piperidin-1-yl-5-(trifluoromethyl)-1,3,4-thiadiazole.
Chemical Property Profile of 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine
Property Insights of 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine. With a topological polar surface area (TPSA) of 57.3 Ų, 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine?
The CAS number of 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine is 694475-26-8.
What is the molecular formula of 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine?
The molecular formula of 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine is C8H10F3N3S.
What is the molecular weight of 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine?
The molecular weight of 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine is 237.05 g/mol.
Where can I buy 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine?
You can request a quote for 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine?
Yes, KEHONG BIO provides custom synthesis services for 1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.