10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine structure

10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine

TL;DR: 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine (CAS 6944-99-6) is a chemical compound with molecular formula C20H22ClF3N2OS and molecular weight 430.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]pyrrolidin-3-ol;hydrochloride

Also Known As: E-0663, E 0663, 3-Pyrrolidinol, 1-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-, monohydrochloride, 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine, 1-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]pyrrolidin-3-ol;hydrochloride

CAS: 6944-99-6
Molecular Formula C20H22ClF3N2OS
Molecular Weight 430.11 g/mol
LogP 5.1866
Topological Polar Surface Area 52.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 4
Exact Mass 430.10934
Heavy Atoms 28
Complexity 506.0

Chemical Identifiers

CAS Number 6944-99-6
SMILES C1CN(CC1O)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F.Cl
InChIKey JSFZWPGUYCFPSV-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine (CAS 6944-99-6), with molecular formula C20H22ClF3N2OS and molecular weight 430.11 g/mol. IUPAC: 1-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]pyrrolidin-3-ol;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine

XLogP
5.1866
TPSA (Topological Polar Surface Area)
52.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
4
Heavy Atoms
28
Complexity
506.0
Exact Mass
430.10934
Monoisotopic Mass
430.10934
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine

The XLogP value of 5.1866 indicates that 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.0 Ų, 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine?

The CAS number of 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine is 6944-99-6.

What is the molecular formula of 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine?

The molecular formula of 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine is C20H22ClF3N2OS.

What is the molecular weight of 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine?

The molecular weight of 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine is 430.11 g/mol.

Where can I buy 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine?

You can request a quote for 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine?

Yes, KEHONG BIO provides custom synthesis services for 10-(3-(3-Hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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