AMG-076 free base structure

AMG-076 free base

TL;DR: AMG-076 free base (CAS 693823-79-9) is a chemical compound with molecular formula C26H33F3N2O2 and molecular weight 462.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[2-[(4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]cyclohexane-1-carboxylic acid

Also Known As: AMG-076 free base, J2.551.466A, Cyclohexanecarboxylic acid, 1-(2-((4aR,11R,11aS)-1,3,4,4a,5,6,11,11a-octahydro-11-methyl-9-(trifluoromethyl)-2H-pyrido(4,3-b)carbazol-2-yl)ethyl)-, (4aR)-2-[2-(1-Carboxycyclohexyl)ethyl]-2,3,4,4abeta,5,6,11,11aalpha-octahydro-9-(trifluoromethyl)-11alpha-methyl-1H-pyrido[4,3-b]carbazole, 1-(2-((4aR,11R,11aS)-11-Methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydro-2H-pyrido[4,3-b]carbazol-2-yl)ethyl)cyclohexane-1-carboxylic acid

CAS: 693823-79-9
Molecular Formula C26H33F3N2O2
Molecular Weight 462.25 g/mol
LogP 6.2096
Topological Polar Surface Area 56.33 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 2
Rotatable Bonds 4
Exact Mass 462.24942
Heavy Atoms 33
Complexity 1038.0669

Chemical Identifiers

CAS Number 693823-79-9
SMILES C[C@@H]1[C@H]2CN(CC[C@@H]2CC3=C1C4=C(N3)C=CC(=C4)C(F)(F)F)CCC5(CCCCC5)C(=O)O

Product Overview

AMG-076 free base (CAS 693823-79-9), with molecular formula C26H33F3N2O2 and molecular weight 462.25 g/mol. IUPAC: 1-[2-[(4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]cyclohexane-1-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of AMG-076 free base

XLogP
6.2096
TPSA (Topological Polar Surface Area)
56.33
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
2
Rotatable Bonds
4
Heavy Atoms
33
Complexity
1038.0669
Exact Mass
462.24942
Monoisotopic Mass
462.24942
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AMG-076 free base

The XLogP value of 6.2096 indicates that AMG-076 free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.33 Ų, AMG-076 free base exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AMG-076 free base has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AMG-076 free base?

The CAS number of AMG-076 free base is 693823-79-9.

What is the molecular formula of AMG-076 free base?

The molecular formula of AMG-076 free base is C26H33F3N2O2.

What is the molecular weight of AMG-076 free base?

The molecular weight of AMG-076 free base is 462.25 g/mol.

Where can I buy AMG-076 free base?

You can request a quote for AMG-076 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AMG-076 free base?

Yes, KEHONG BIO provides custom synthesis services for AMG-076 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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