Dexamethasone hydrochloride
TL;DR: Dexamethasone hydrochloride (CAS 69351-57-1) is a chemical compound with molecular formula C22H30ClFO5 and molecular weight 428.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,10S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;hydrochloride
Also Known As: Dexamethasone hydrochloride, 3-Cyclohexene-1-carboxamide, 1-methyl-, (8S,10S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one hydrochloride, (9xi)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione--hydrogen chloride (1/1), 9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione--hydrogen chloride (1/1)
| Molecular Formula | C22H30ClFO5 |
|---|---|
| Molecular Weight | 428.18 g/mol |
| LogP | 2.3175 |
| Topological Polar Surface Area | 94.8 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 428.17657 |
| Heavy Atoms | 29 |
| Complexity | 805.0 |
Chemical Identifiers
| CAS Number | 69351-57-1 |
|---|---|
| SMILES | CC1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C3(C(C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C.Cl |
| InChIKey | OHILSKSRDDTCIR-CQIRMVKISA-N |
Product Overview
Dexamethasone hydrochloride (CAS 69351-57-1), with molecular formula C22H30ClFO5 and molecular weight 428.18 g/mol. IUPAC: (8S,10S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;hydrochloride.
Chemical Property Profile of Dexamethasone hydrochloride
Property Insights of Dexamethasone hydrochloride
The XLogP value of 2.3175 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dexamethasone hydrochloride. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Dexamethasone hydrochloride. Following Lipinski's Rule of Five, Dexamethasone hydrochloride has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Dexamethasone hydrochloride?
The CAS number of Dexamethasone hydrochloride is 69351-57-1.
What is the molecular formula of Dexamethasone hydrochloride?
The molecular formula of Dexamethasone hydrochloride is C22H30ClFO5.
What is the molecular weight of Dexamethasone hydrochloride?
The molecular weight of Dexamethasone hydrochloride is 428.18 g/mol.
Where can I buy Dexamethasone hydrochloride?
You can request a quote for Dexamethasone hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Dexamethasone hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Dexamethasone hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.