(4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
TL;DR: (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone (CAS 692284-67-6) is a chemical compound with molecular formula C16H12ClF2NO and molecular weight 307.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Also Known As: A3542/0150123, (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone, (4-chloro-2,3-difluorophenyl)(3,4-dihydroisoquinolin-2(1H)-yl)methanone, 2-(4-CHLORO-2,3-DIFLUOROBENZOYL)-1,2,3,4-TETRAHYDROISOQUINOLINE
| Molecular Formula | C16H12ClF2NO |
|---|---|
| Molecular Weight | 307.06 g/mol |
| LogP | 3.8167 |
| Topological Polar Surface Area | 20.31 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 307.05756 |
| Heavy Atoms | 21 |
| Complexity | 717.41833 |
Chemical Identifiers
| CAS Number | 692284-67-6 |
|---|---|
| SMILES | C1CN(CC2=CC=CC=C21)C(=O)C3=C(C(=C(C=C3)Cl)F)F |
Product Overview
(4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone (CAS 692284-67-6), with molecular formula C16H12ClF2NO and molecular weight 307.06 g/mol. IUPAC: (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone.
Chemical Property Profile of (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Property Insights of (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
The XLogP value of 3.8167 indicates that (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.31 Ų, (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone?
The CAS number of (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone is 692284-67-6.
What is the molecular formula of (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone?
The molecular formula of (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone is C16H12ClF2NO.
What is the molecular weight of (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone?
The molecular weight of (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone is 307.06 g/mol.
Where can I buy (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone?
You can request a quote for (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone?
Yes, KEHONG BIO provides custom synthesis services for (4-chloro-2,3-difluorophenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.