Bleomycin bapp
TL;DR: Bleomycin bapp (CAS 69177-41-9) is a chemical compound with molecular formula C60H95N19O21S2 and molecular weight 1481.64 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-[3-[3-(butylamino)propylamino]propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
Also Known As: Bleomycin bapp, Bleomycin-BAPP, N1-(3-((3-(Butylamino)propyl)amino)propyl)bleomycinamide, Bleomycinamide, N(sup 1)-(3-((3-(butylamino)propyl)amino)propyl)-, [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-[3-[3-(butylamino)propylamino]propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
| Molecular Formula | C60H95N19O21S2 |
|---|---|
| Molecular Weight | 1481.64 g/mol |
| LogP | -7.4 |
| Topological Polar Surface Area | 708.0 Ų |
| Hydrogen Bond Donors | 22 |
| Hydrogen Bond Acceptors | 33 |
| Rotatable Bonds | 43 |
| Exact Mass | 1481.6392 |
| Heavy Atoms | 102 |
| Complexity | 2670.0 |
Chemical Identifiers
| CAS Number | 69177-41-9 |
|---|---|
| SMILES | CCCCNCCCNCCCNC(=O)C1=CSC(=N1)C2=CSC(=N2)CCNC(=O)C(C(C)O)NC(=O)C(C)C(C(C)NC(=O)C(C(C3=CN=CN3)OC4C(C(C(C(O4)CO)O)O)OC5C(C(C(C(O5)CO)O)OC(=O)N)O)NC(=O)C6=C(C(=NC(=N6)C(CC(=O)N)NCC(C(=O)N)N)N)C)O |
| InChIKey | FLFCXZBJUUSBFH-UHFFFAOYSA-N |
Product Overview
Bleomycin bapp (CAS 69177-41-9), with molecular formula C60H95N19O21S2 and molecular weight 1481.64 g/mol. IUPAC: [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-[3-[3-(butylamino)propylamino]propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate.
Chemical Property Profile of Bleomycin bapp
Property Insights of Bleomycin bapp
The XLogP value of -7.4 indicates that Bleomycin bapp is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 708.0 Ų indicates high polarity, suggesting Bleomycin bapp may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bleomycin bapp has 22 hydrogen bond donor(s) and 33 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bleomycin bapp?
The CAS number of Bleomycin bapp is 69177-41-9.
What is the molecular formula of Bleomycin bapp?
The molecular formula of Bleomycin bapp is C60H95N19O21S2.
What is the molecular weight of Bleomycin bapp?
The molecular weight of Bleomycin bapp is 1481.64 g/mol.
Where can I buy Bleomycin bapp?
You can request a quote for Bleomycin bapp directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bleomycin bapp?
Yes, KEHONG BIO provides custom synthesis services for Bleomycin bapp and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.