Losindole
TL;DR: Losindole (CAS 69175-77-5) is a chemical compound with molecular formula C19H20ClN and molecular weight 297.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3aS,4R,9aR)-6-chloro-2-methyl-4-phenyl-1,3,3a,4,9,9a-hexahydrobenzo[f]isoindole
Also Known As: Losindole, Losindole [INN], 4'-Demethyleucomin, (3aS,4R,9aR)-6-chloro-2-methyl-4-phenyl-1,3,3a,4,9,9a-hexahydrobenzo[f]isoindole, (3aS,4R,9aR)-6-chloro-2-methyl-4-phenyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]isoindole
| Molecular Formula | C19H20ClN |
|---|---|
| Molecular Weight | 297.13 g/mol |
| LogP | 4.2058 |
| Topological Polar Surface Area | 3.24 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 297.12842 |
| Heavy Atoms | 21 |
| Complexity | 651.87085 |
Chemical Identifiers
| CAS Number | 69175-77-5 |
|---|---|
| SMILES | CN1C[C@@H]2CC3=C(C=C(C=C3)Cl)[C@H]([C@@H]2C1)C4=CC=CC=C4 |
Product Overview
Losindole (CAS 69175-77-5), with molecular formula C19H20ClN and molecular weight 297.13 g/mol. IUPAC: (3aS,4R,9aR)-6-chloro-2-methyl-4-phenyl-1,3,3a,4,9,9a-hexahydrobenzo[f]isoindole.
Chemical Property Profile of Losindole
Property Insights of Losindole
The XLogP value of 4.2058 indicates that Losindole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.24 Ų, Losindole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Losindole has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Losindole?
The CAS number of Losindole is 69175-77-5.
What is the molecular formula of Losindole?
The molecular formula of Losindole is C19H20ClN.
What is the molecular weight of Losindole?
The molecular weight of Losindole is 297.13 g/mol.
Where can I buy Losindole?
You can request a quote for Losindole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Losindole?
Yes, KEHONG BIO provides custom synthesis services for Losindole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.