(+)-Naloxone hydrochloride
TL;DR: (+)-Naloxone hydrochloride (CAS 69133-14-8) is a chemical compound with molecular formula C19H22ClNO4 and molecular weight 363.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4S,4aR,7aS,12bR)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride
Also Known As: (+)-Naloxone hydrochloride, Naloxone hydrochloride, d-Naloxone hydrochloride, Naloxone hydrochloride, (+)-, MCV 4152
| Molecular Formula | C19H22ClNO4 |
|---|---|
| Molecular Weight | 363.12 g/mol |
| LogP | 1.7232 |
| Topological Polar Surface Area | 70.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 363.12375 |
| Heavy Atoms | 25 |
| Complexity | 780.93274 |
Chemical Identifiers
| CAS Number | 69133-14-8 |
|---|---|
| SMILES | C=CCN1CC[C@@]23[C@H]4C(=O)CC[C@@]2([C@@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl |
Product Overview
(+)-Naloxone hydrochloride (CAS 69133-14-8), with molecular formula C19H22ClNO4 and molecular weight 363.12 g/mol. IUPAC: (4S,4aR,7aS,12bR)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride.
Chemical Property Profile of (+)-Naloxone hydrochloride
Property Insights of (+)-Naloxone hydrochloride
The XLogP value of 1.7232 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (+)-Naloxone hydrochloride. The TPSA of 70.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (+)-Naloxone hydrochloride. Following Lipinski's Rule of Five, (+)-Naloxone hydrochloride has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (+)-Naloxone hydrochloride?
The CAS number of (+)-Naloxone hydrochloride is 69133-14-8.
What is the molecular formula of (+)-Naloxone hydrochloride?
The molecular formula of (+)-Naloxone hydrochloride is C19H22ClNO4.
What is the molecular weight of (+)-Naloxone hydrochloride?
The molecular weight of (+)-Naloxone hydrochloride is 363.12 g/mol.
Where can I buy (+)-Naloxone hydrochloride?
You can request a quote for (+)-Naloxone hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (+)-Naloxone hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for (+)-Naloxone hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.