4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine
TL;DR: 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine (CAS 690696-21-0) is a chemical compound with molecular formula C14H11FN4S and molecular weight 286.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine
Also Known As: BAS 04880431, AP-048/41203042, 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine, N-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]pyrimidin-2-amine, [4-(4-Fluoro-3-methyl-phenyl)-thiazol-2-yl]-pyrimidin-2-yl-amine
| Molecular Formula | C14H11FN4S |
|---|---|
| Molecular Weight | 286.07 g/mol |
| LogP | 3.79122 |
| Topological Polar Surface Area | 50.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 286.06885 |
| Heavy Atoms | 20 |
| Complexity | 727.04865 |
Chemical Identifiers
| CAS Number | 690696-21-0 |
|---|---|
| SMILES | CC1=C(C=CC(=C1)C2=CSC(=N2)NC3=NC=CC=N3)F |
Product Overview
4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine (CAS 690696-21-0), with molecular formula C14H11FN4S and molecular weight 286.07 g/mol. IUPAC: 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine.
Chemical Property Profile of 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine
Property Insights of 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine
The XLogP value of 3.79122 indicates that 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.7 Ų, 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine?
The CAS number of 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine is 690696-21-0.
What is the molecular formula of 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine?
The molecular formula of 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine is C14H11FN4S.
What is the molecular weight of 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine?
The molecular weight of 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine is 286.07 g/mol.
Where can I buy 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine?
You can request a quote for 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.