K297-0828
TL;DR: K297-0828 (CAS 688356-08-3) is a chemical compound with molecular formula C24H19F2N3O2S and molecular weight 451.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3-[[4-(3,4-difluoroanilino)quinazolin-2-yl]sulfanylmethyl]-4-methoxyphenyl]ethanone
Also Known As: K297-0828, 1-{3-[({4-[(3,4-difluorophenyl)amino]quinazolin-2-yl}sulfanyl)methyl]-4-methoxyphenyl}ethan-1-one, F6548-4703, 1-(3-(((4-((3,4-difluorophenyl)amino)quinazolin-2-yl)thio)methyl)-4-methoxyphenyl)ethanone, 1-[3-[[4-(3,4-difluoroanilino)quinazolin-2-yl]sulfanylmethyl]-4-methoxyphenyl]ethanone
| Molecular Formula | C24H19F2N3O2S |
|---|---|
| Molecular Weight | 451.12 g/mol |
| LogP | 6.1551 |
| Topological Polar Surface Area | 64.11 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 451.1166 |
| Heavy Atoms | 32 |
| Complexity | 1313.9152 |
Chemical Identifiers
| CAS Number | 688356-08-3 |
|---|---|
| SMILES | CC(=O)C1=CC(=C(C=C1)OC)CSC2=NC3=CC=CC=C3C(=N2)NC4=CC(=C(C=C4)F)F |
Product Overview
K297-0828 (CAS 688356-08-3), with molecular formula C24H19F2N3O2S and molecular weight 451.12 g/mol. IUPAC: 1-[3-[[4-(3,4-difluoroanilino)quinazolin-2-yl]sulfanylmethyl]-4-methoxyphenyl]ethanone.
Chemical Property Profile of K297-0828
Property Insights of K297-0828
The XLogP value of 6.1551 indicates that K297-0828 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.11 Ų falls within the moderate polarity range, balancing permeability and solubility for K297-0828. Following Lipinski's Rule of Five, K297-0828 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of K297-0828?
The CAS number of K297-0828 is 688356-08-3.
What is the molecular formula of K297-0828?
The molecular formula of K297-0828 is C24H19F2N3O2S.
What is the molecular weight of K297-0828?
The molecular weight of K297-0828 is 451.12 g/mol.
Where can I buy K297-0828?
You can request a quote for K297-0828 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for K297-0828?
Yes, KEHONG BIO provides custom synthesis services for K297-0828 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.