6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide
TL;DR: 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide (CAS 688028-45-7) is a chemical compound with molecular formula C18H12BrN3OS2 and molecular weight 428.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide
Also Known As: 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide, 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-(2-thienyl)-4-quinolinecarboxamide, (6-bromo-8-methyl-2-(2-thienyl)(4-quinolyl))-N-(1,3-thiazol-2-yl)carboxamide, 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-(thiophen-2-yl)quinoline-4-carboxamide
| Molecular Formula | C18H12BrN3OS2 |
|---|---|
| Molecular Weight | 428.96 g/mol |
| LogP | 5.74302 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 428.9605 |
| Heavy Atoms | 25 |
| Complexity | 1059.822 |
Chemical Identifiers
| CAS Number | 688028-45-7 |
|---|---|
| SMILES | CC1=CC(=CC2=C1N=C(C=C2C(=O)NC3=NC=CS3)C4=CC=CS4)Br |
Product Overview
6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide (CAS 688028-45-7), with molecular formula C18H12BrN3OS2 and molecular weight 428.96 g/mol. IUPAC: 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide.
Chemical Property Profile of 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide
Property Insights of 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide
The XLogP value of 5.74302 indicates that 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide?
The CAS number of 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide is 688028-45-7.
What is the molecular formula of 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide?
The molecular formula of 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide is C18H12BrN3OS2.
What is the molecular weight of 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide?
The molecular weight of 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide is 428.96 g/mol.
Where can I buy 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide?
You can request a quote for 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 6-bromo-8-methyl-N-(1,3-thiazol-2-yl)-2-thiophen-2-ylquinoline-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.