Diethyl 2-ethyl-2-(p-tolyl)malonate structure

Diethyl 2-ethyl-2-(p-tolyl)malonate

TL;DR: Diethyl 2-ethyl-2-(p-tolyl)malonate (CAS 68692-80-8) is a chemical compound with molecular formula C16H22O4 and molecular weight 278.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

diethyl 2-ethyl-2-(4-methylphenyl)propanedioate

Also Known As: Diethyl 2-ethyl-2-(p-tolyl)malonate, 3-Ethyl-2-methyl-3-pentanol, EINECS 272-082-8, Diethyl2-ethyl-2-(p-tolyl)malonate, diethyl 2-ethyl-2-(4-methylphenyl)propanedioate

CAS: 68692-80-8
Molecular Formula C16H22O4
Molecular Weight 278.15 g/mol
LogP 2.76902
Topological Polar Surface Area 52.6 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 6
Exact Mass 278.1518
Heavy Atoms 20
Complexity 443.87015

Chemical Identifiers

CAS Number 68692-80-8
SMILES CCC(C1=CC=C(C=C1)C)(C(=O)OCC)C(=O)OCC

Product Overview

Diethyl 2-ethyl-2-(p-tolyl)malonate (CAS 68692-80-8), with molecular formula C16H22O4 and molecular weight 278.15 g/mol. IUPAC: diethyl 2-ethyl-2-(4-methylphenyl)propanedioate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Diethyl 2-ethyl-2-(p-tolyl)malonate

XLogP
2.76902
TPSA (Topological Polar Surface Area)
52.6
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
6
Heavy Atoms
20
Complexity
443.87015
Exact Mass
278.1518
Monoisotopic Mass
278.1518
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Diethyl 2-ethyl-2-(p-tolyl)malonate

The XLogP value of 2.76902 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Diethyl 2-ethyl-2-(p-tolyl)malonate. With a topological polar surface area (TPSA) of 52.6 Ų, Diethyl 2-ethyl-2-(p-tolyl)malonate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Diethyl 2-ethyl-2-(p-tolyl)malonate has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Diethyl 2-ethyl-2-(p-tolyl)malonate?

The CAS number of Diethyl 2-ethyl-2-(p-tolyl)malonate is 68692-80-8.

What is the molecular formula of Diethyl 2-ethyl-2-(p-tolyl)malonate?

The molecular formula of Diethyl 2-ethyl-2-(p-tolyl)malonate is C16H22O4.

What is the molecular weight of Diethyl 2-ethyl-2-(p-tolyl)malonate?

The molecular weight of Diethyl 2-ethyl-2-(p-tolyl)malonate is 278.15 g/mol.

Where can I buy Diethyl 2-ethyl-2-(p-tolyl)malonate?

You can request a quote for Diethyl 2-ethyl-2-(p-tolyl)malonate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Diethyl 2-ethyl-2-(p-tolyl)malonate?

Yes, KEHONG BIO provides custom synthesis services for Diethyl 2-ethyl-2-(p-tolyl)malonate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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