Mefloquine hydrochloride
TL;DR: Mefloquine hydrochloride (CAS 68682-28-0) is a chemical compound with molecular formula C17H17ClF6N2O and molecular weight 414.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[2,8-bis(trifluoromethyl)quinolin-4-yl]-piperidin-2-ylmethanol;hydrochloride
Also Known As: Mefloquine hydrochloride, mefloquine, Mephaquin, Mefloquine HCL, Lariam
| Molecular Formula | C17H17ClF6N2O |
|---|---|
| Molecular Weight | 414.09 g/mol |
| LogP | 4.8697 |
| Topological Polar Surface Area | 45.2 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 414.09335 |
| Heavy Atoms | 27 |
| Complexity | 483.0 |
Chemical Identifiers
| CAS Number | 68682-28-0 |
|---|---|
| SMILES | C1CCNC(C1)C(C2=CC(=NC3=C2C=CC=C3C(F)(F)F)C(F)(F)F)O.Cl |
| InChIKey | WESWYMRNZNDGBX-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 12 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Mefloquine hydrochloride (CAS 68682-28-0), with molecular formula C17H17ClF6N2O and molecular weight 414.09 g/mol. IUPAC: [2,8-bis(trifluoromethyl)quinolin-4-yl]-piperidin-2-ylmethanol;hydrochloride.
Chemical Property Profile of Mefloquine hydrochloride
Property Insights of Mefloquine hydrochloride
The XLogP value of 4.8697 indicates that Mefloquine hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.2 Ų, Mefloquine hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Mefloquine hydrochloride has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Mefloquine hydrochloride?
The CAS number of Mefloquine hydrochloride is 68682-28-0.
What is the molecular formula of Mefloquine hydrochloride?
The molecular formula of Mefloquine hydrochloride is C17H17ClF6N2O.
What is the molecular weight of Mefloquine hydrochloride?
The molecular weight of Mefloquine hydrochloride is 414.09 g/mol.
Where can I buy Mefloquine hydrochloride?
You can request a quote for Mefloquine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Mefloquine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Mefloquine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.