![5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one structure](/static/products/6867/686726-23-8.webp)
5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one
TL;DR: 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one (CAS 686726-23-8) is a chemical compound with molecular formula C18H16FNO and molecular weight 281.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-3-[(4-propan-2-ylphenyl)methylidene]-1H-indol-2-one
Also Known As: 5-fluoro-3-[(4-propan-2-ylphenyl)methylidene]-1H-indol-2-one, 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one, 5-Fluoro-3-{[4-(propan-2-yl)phenyl]methylidene}-1,3-dihydro-2H-indol-2-one
| Molecular Formula | C18H16FNO |
|---|---|
| Molecular Weight | 281.12 g/mol |
| LogP | 4.4418 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 281.12158 |
| Heavy Atoms | 21 |
| Complexity | 729.3836 |
Chemical Identifiers
| CAS Number | 686726-23-8 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)C=C2C3=C(C=CC(=C3)F)NC2=O |
Product Overview
5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one (CAS 686726-23-8), with molecular formula C18H16FNO and molecular weight 281.12 g/mol. IUPAC: 5-fluoro-3-[(4-propan-2-ylphenyl)methylidene]-1H-indol-2-one.
Chemical Property Profile of 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one
Property Insights of 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one
The XLogP value of 4.4418 indicates that 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one?
The CAS number of 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one is 686726-23-8.
What is the molecular formula of 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one?
The molecular formula of 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one is C18H16FNO.
What is the molecular weight of 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one?
The molecular weight of 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one is 281.12 g/mol.
Where can I buy 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one?
You can request a quote for 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 5-Fluoro-1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.