4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine
TL;DR: 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine (CAS 686725-05-3) is a chemical compound with molecular formula C17H12ClF3N4 and molecular weight 364.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-chlorophenyl)-N-(pyridin-3-ylmethyl)-6-(trifluoromethyl)pyrimidin-2-amine
Also Known As: 4-(4-chlorophenyl)-N-(pyridin-3-ylmethyl)-6-(trifluoromethyl)pyrimidin-2-amine, 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine, [4-(4-Chloro-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-pyridin-3-ylmethyl-amine, [4-(4-chlorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl](3-pyridylmethyl)amine
| Molecular Formula | C17H12ClF3N4 |
|---|---|
| Molecular Weight | 364.07 g/mol |
| LogP | 4.8229 |
| Topological Polar Surface Area | 50.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 364.07025 |
| Heavy Atoms | 25 |
| Complexity | 852.01697 |
Chemical Identifiers
| CAS Number | 686725-05-3 |
|---|---|
| SMILES | C1=CC(=CN=C1)CNC2=NC(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)Cl |
Product Overview
4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine (CAS 686725-05-3), with molecular formula C17H12ClF3N4 and molecular weight 364.07 g/mol. IUPAC: 4-(4-chlorophenyl)-N-(pyridin-3-ylmethyl)-6-(trifluoromethyl)pyrimidin-2-amine.
Chemical Property Profile of 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine
Property Insights of 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine
The XLogP value of 4.8229 indicates that 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.7 Ų, 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine?
The CAS number of 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine is 686725-05-3.
What is the molecular formula of 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine?
The molecular formula of 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine is C17H12ClF3N4.
What is the molecular weight of 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine?
The molecular weight of 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine is 364.07 g/mol.
Where can I buy 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine?
You can request a quote for 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.