co-Amilozide structure

co-Amilozide

TL;DR: co-Amilozide (CAS 68529-45-3) is a chemical compound with molecular formula C13H16Cl2N10O5S2 and molecular weight 526.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide;3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide

Also Known As: co-Amilozide, Moduretic, 1 Syyetic, Amiloride mixture with hydrochlorothiazide, Amiloride hydrochloride, hydrochlorothiazide

CAS: 68529-45-3
Molecular Formula C13H16Cl2N10O5S2
Molecular Weight 526.01 g/mol
LogP -1.64
Topological Polar Surface Area 294.0 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 12
Rotatable Bonds 2
Exact Mass 526.0124
Heavy Atoms 32
Complexity 773.0

Chemical Identifiers

CAS Number 68529-45-3
SMILES C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl.C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N
InChIKey GRASNTSYMCINOF-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (36 patents)

Product Overview

co-Amilozide (CAS 68529-45-3), with molecular formula C13H16Cl2N10O5S2 and molecular weight 526.01 g/mol. IUPAC: 6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide;3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of co-Amilozide

XLogP
-1.64
TPSA (Topological Polar Surface Area)
294.0
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
12
Rotatable Bonds
2
Heavy Atoms
32
Complexity
773.0
Exact Mass
526.0124
Monoisotopic Mass
526.0124
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of co-Amilozide

The XLogP value of -1.64 indicates that co-Amilozide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 294.0 Ų indicates high polarity, suggesting co-Amilozide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, co-Amilozide has 7 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of co-Amilozide?

The CAS number of co-Amilozide is 68529-45-3.

What is the molecular formula of co-Amilozide?

The molecular formula of co-Amilozide is C13H16Cl2N10O5S2.

What is the molecular weight of co-Amilozide?

The molecular weight of co-Amilozide is 526.01 g/mol.

Where can I buy co-Amilozide?

You can request a quote for co-Amilozide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for co-Amilozide?

Yes, KEHONG BIO provides custom synthesis services for co-Amilozide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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