(Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate
TL;DR: (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate (CAS 685121-70-4) is a chemical compound with molecular formula C20H24N2O5S and molecular weight 404.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 1-[(5Z)-5-[(3-ethoxy-4-hydroxyphenyl)methylidene]-4-oxo-1,3-thiazol-2-yl]piperidine-3-carboxylate
Also Known As: (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate, ethyl 1-[(5Z)-5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]piperidine-3-carboxylate, ethyl 1-[(5Z)-5-[(3-ethoxy-4-hydroxyphenyl)methylidene]-4-oxo-1,3-thiazol-2-yl]piperidine-3-carboxylate, ETHYL 1-[(5Z)-5-[(3-ETHOXY-4-HYDROXYPHENYL)METHYLIDENE]-4-OXO-4,5-DIHYDRO-1,3-THIAZOL-2-YL]PIPERIDINE-3-CARBOXYLATE
| Molecular Formula | C20H24N2O5S |
|---|---|
| Molecular Weight | 404.14 g/mol |
| LogP | 3.0363 |
| Topological Polar Surface Area | 88.43 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 404.1406 |
| Heavy Atoms | 28 |
| Complexity | 820.8141 |
Chemical Identifiers
| CAS Number | 685121-70-4 |
|---|---|
| SMILES | CCOC1=C(C=CC(=C1)/C=C\2/C(=O)N=C(S2)N3CCCC(C3)C(=O)OCC)O |
Product Overview
(Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate (CAS 685121-70-4), with molecular formula C20H24N2O5S and molecular weight 404.14 g/mol. IUPAC: ethyl 1-[(5Z)-5-[(3-ethoxy-4-hydroxyphenyl)methylidene]-4-oxo-1,3-thiazol-2-yl]piperidine-3-carboxylate.
Chemical Property Profile of (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate
Property Insights of (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate
The XLogP value of 3.0363 indicates that (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.43 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate. Following Lipinski's Rule of Five, (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate?
The CAS number of (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate is 685121-70-4.
What is the molecular formula of (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate?
The molecular formula of (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate is C20H24N2O5S.
What is the molecular weight of (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate?
The molecular weight of (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate is 404.14 g/mol.
Where can I buy (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate?
You can request a quote for (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for (Z)-ethyl 1-(5-(3-ethoxy-4-hydroxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)piperidine-3-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.