US11279687, Compound 421
TL;DR: US11279687, Compound 421 (CAS 684231-74-1) is a chemical compound with molecular formula C24H20N4O3S2 and molecular weight 476.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)-N-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzamide
Also Known As: US11279687, Compound 421, N-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]-4-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)benzamide, F1166-0023, 4-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)-N-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzamide, 4-((3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-N-(4-(pyridin-3-yl)thiazol-2-yl)benzamide
| Molecular Formula | C24H20N4O3S2 |
|---|---|
| Molecular Weight | 476.10 g/mol |
| LogP | 4.2044 |
| Topological Polar Surface Area | 92.26 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 476.0977 |
| Heavy Atoms | 33 |
| Complexity | 1401.1721 |
Chemical Identifiers
| CAS Number | 684231-74-1 |
|---|---|
| SMILES | C1CN(CC2=CC=CC=C21)S(=O)(=O)C3=CC=C(C=C3)C(=O)NC4=NC(=CS4)C5=CN=CC=C5 |
Product Overview
US11279687, Compound 421 (CAS 684231-74-1), with molecular formula C24H20N4O3S2 and molecular weight 476.10 g/mol. IUPAC: 4-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)-N-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzamide.
Chemical Property Profile of US11279687, Compound 421
Property Insights of US11279687, Compound 421
The XLogP value of 4.2044 indicates that US11279687, Compound 421 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 92.26 Ų falls within the moderate polarity range, balancing permeability and solubility for US11279687, Compound 421. Following Lipinski's Rule of Five, US11279687, Compound 421 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of US11279687, Compound 421?
The CAS number of US11279687, Compound 421 is 684231-74-1.
What is the molecular formula of US11279687, Compound 421?
The molecular formula of US11279687, Compound 421 is C24H20N4O3S2.
What is the molecular weight of US11279687, Compound 421?
The molecular weight of US11279687, Compound 421 is 476.10 g/mol.
Where can I buy US11279687, Compound 421?
You can request a quote for US11279687, Compound 421 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for US11279687, Compound 421?
Yes, KEHONG BIO provides custom synthesis services for US11279687, Compound 421 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.