F1110-0372
TL;DR: F1110-0372 (CAS 683258-46-0) is a chemical compound with molecular formula C19H13ClFN3OS and molecular weight 385.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(3-chloro-4-fluoroanilino)-2-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]prop-2-enenitrile
Also Known As: F1110-0372, (E)-3-((3-chloro-4-fluorophenyl)amino)-2-(4-(4-methoxyphenyl)thiazol-2-yl)acrylonitrile, (E)-3-(3-chloro-4-fluoroanilino)-2-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]prop-2-enenitrile, (2E)-3-[(3-chloro-4-fluorophenyl)amino]-2-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]prop-2-enenitrile, 3-((3-Chloro-4-fluorophenyl)amino)-2-(4-(4-methoxyphenyl)thiazol-2-yl)acrylonitrile
| Molecular Formula | C19H13ClFN3OS |
|---|---|
| Molecular Weight | 385.05 g/mol |
| LogP | 5.58778 |
| Topological Polar Surface Area | 57.94 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 385.0452 |
| Heavy Atoms | 26 |
| Complexity | 992.764 |
Chemical Identifiers
| CAS Number | 683258-46-0 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=CSC(=N2)/C(=C/NC3=CC(=C(C=C3)F)Cl)/C#N |
Product Overview
F1110-0372 (CAS 683258-46-0), with molecular formula C19H13ClFN3OS and molecular weight 385.05 g/mol. IUPAC: (E)-3-(3-chloro-4-fluoroanilino)-2-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]prop-2-enenitrile.
Chemical Property Profile of F1110-0372
Property Insights of F1110-0372
The XLogP value of 5.58778 indicates that F1110-0372 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.94 Ų, F1110-0372 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1110-0372 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1110-0372?
The CAS number of F1110-0372 is 683258-46-0.
What is the molecular formula of F1110-0372?
The molecular formula of F1110-0372 is C19H13ClFN3OS.
What is the molecular weight of F1110-0372?
The molecular weight of F1110-0372 is 385.05 g/mol.
Where can I buy F1110-0372?
You can request a quote for F1110-0372 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1110-0372?
Yes, KEHONG BIO provides custom synthesis services for F1110-0372 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.