5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole
TL;DR: 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole (CAS 683203-76-1) is a chemical compound with molecular formula C18H18FN3O2S and molecular weight 359.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-1-(4-piperazin-1-ylphenyl)sulfonylindole
Also Known As: 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole, 5-Fluoro-1-((4-(piperazin-1-yl)phenyl)sulfonyl)-1H-indole, 5-fluoro-1-(4-piperazin-1-ylphenyl)sulfonyl-indole, 1H-Indole, 5-fluoro-1-[[4-(1-piperazinyl)phenyl]sulfonyl]-, 5-Fluoro-1-[4-(piperazin-1-yl)benzene-1-sulfonyl]-1H-indole
| Molecular Formula | C18H18FN3O2S |
|---|---|
| Molecular Weight | 359.11 g/mol |
| LogP | 2.427 |
| Topological Polar Surface Area | 54.34 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 359.11038 |
| Heavy Atoms | 25 |
| Complexity | 1006.4821 |
Chemical Identifiers
| CAS Number | 683203-76-1 |
|---|---|
| SMILES | C1CN(CCN1)C2=CC=C(C=C2)S(=O)(=O)N3C=CC4=C3C=CC(=C4)F |
Product Overview
5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole (CAS 683203-76-1), with molecular formula C18H18FN3O2S and molecular weight 359.11 g/mol. IUPAC: 5-fluoro-1-(4-piperazin-1-ylphenyl)sulfonylindole.
Chemical Property Profile of 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole
Property Insights of 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole
The XLogP value of 2.427 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole. With a topological polar surface area (TPSA) of 54.34 Ų, 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole?
The CAS number of 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole is 683203-76-1.
What is the molecular formula of 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole?
The molecular formula of 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole is C18H18FN3O2S.
What is the molecular weight of 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole?
The molecular weight of 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole is 359.11 g/mol.
Where can I buy 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole?
You can request a quote for 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole?
Yes, KEHONG BIO provides custom synthesis services for 5-Fluoro-1-(4-piperazin-1-yl-benzenesulfonyl)-1H-indole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.