1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol
TL;DR: 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol (CAS 681460-22-0) is a chemical compound with molecular formula C23H21NO3S and molecular weight 391.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol
Also Known As: 1-naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol, 1-(2-naphthylsulfonyl)-4-(phenylethynyl)piperidin-4-ol (en)4
| Molecular Formula | C23H21NO3S |
|---|---|
| Molecular Weight | 391.12 g/mol |
| LogP | 3.4071 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 391.1242 |
| Heavy Atoms | 28 |
| Complexity | 1152.4218 |
Chemical Identifiers
| CAS Number | 681460-22-0 |
|---|---|
| SMILES | C1CN(CCC1(C#CC2=CC=CC=C2)O)S(=O)(=O)C3=CC4=CC=CC=C4C=C3 |
Product Overview
1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol (CAS 681460-22-0), with molecular formula C23H21NO3S and molecular weight 391.12 g/mol. IUPAC: 1-naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol.
Chemical Property Profile of 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol
Property Insights of 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol
The XLogP value of 3.4071 indicates that 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol?
The CAS number of 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol is 681460-22-0.
What is the molecular formula of 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol?
The molecular formula of 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol is C23H21NO3S.
What is the molecular weight of 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol?
The molecular weight of 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol is 391.12 g/mol.
Where can I buy 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol?
You can request a quote for 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol?
Yes, KEHONG BIO provides custom synthesis services for 1-Naphthalen-2-ylsulfonyl-4-(2-phenylethynyl)piperidin-4-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.