GW827106X
TL;DR: GW827106X (CAS 681432-07-5) is a chemical compound with molecular formula C25H20N6O3 and molecular weight 452.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-[2-(4-methoxyphenyl)pyrazolo[1,5-b]pyridazin-3-yl]pyrimidin-2-amine
Also Known As: GW827106X, pyrazolo[1,5-b]pyridazine deriv. 72, SDCCGGSK-0000349.P001, AB01092297-01, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-[2-(4-methoxyphenyl)pyrazolo[1,5-b]pyridazin-3-yl]pyrimidin-2-amine
| Molecular Formula | C25H20N6O3 |
|---|---|
| Molecular Weight | 452.16 g/mol |
| LogP | 4.3767 |
| Topological Polar Surface Area | 95.69 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 452.1597 |
| Heavy Atoms | 34 |
| Complexity | 1482.317 |
Chemical Identifiers
| CAS Number | 681432-07-5 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=NN3C(=C2C4=NC(=NC=C4)NC5=CC6=C(C=C5)OCCO6)C=CC=N3 |
Product Overview
GW827106X (CAS 681432-07-5), with molecular formula C25H20N6O3 and molecular weight 452.16 g/mol. IUPAC: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-[2-(4-methoxyphenyl)pyrazolo[1,5-b]pyridazin-3-yl]pyrimidin-2-amine.
Chemical Property Profile of GW827106X
Property Insights of GW827106X
The XLogP value of 4.3767 indicates that GW827106X is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.69 Ų falls within the moderate polarity range, balancing permeability and solubility for GW827106X. Following Lipinski's Rule of Five, GW827106X has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of GW827106X?
The CAS number of GW827106X is 681432-07-5.
What is the molecular formula of GW827106X?
The molecular formula of GW827106X is C25H20N6O3.
What is the molecular weight of GW827106X?
The molecular weight of GW827106X is 452.16 g/mol.
Where can I buy GW827106X?
You can request a quote for GW827106X directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for GW827106X?
Yes, KEHONG BIO provides custom synthesis services for GW827106X and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.