F0545-0366 structure

F0545-0366

TL;DR: F0545-0366 (CAS 681275-85-4) is a chemical compound with molecular formula C25H21F3N2OS and molecular weight 454.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[1-[(3-methylphenyl)methyl]indol-3-yl]sulfanyl-N-[2-(trifluoromethyl)phenyl]acetamide

Also Known As: F0545-0366, 2-((1-(3-methylbenzyl)-1H-indol-3-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide, 2-({1-[(3-methylphenyl)methyl]-1H-indol-3-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide, 2-[1-[(3-methylphenyl)methyl]indol-3-yl]sulfanyl-N-[2-(trifluoromethyl)phenyl]acetamide

CAS: 681275-85-4
Molecular Formula C25H21F3N2OS
Molecular Weight 454.13 g/mol
LogP 6.74762
Topological Polar Surface Area 34.03 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 6
Exact Mass 454.13266
Heavy Atoms 32
Complexity 1263.5197

Chemical Identifiers

CAS Number 681275-85-4
SMILES CC1=CC(=CC=C1)CN2C=C(C3=CC=CC=C32)SCC(=O)NC4=CC=CC=C4C(F)(F)F

Product Overview

F0545-0366 (CAS 681275-85-4), with molecular formula C25H21F3N2OS and molecular weight 454.13 g/mol. IUPAC: 2-[1-[(3-methylphenyl)methyl]indol-3-yl]sulfanyl-N-[2-(trifluoromethyl)phenyl]acetamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F0545-0366

XLogP
6.74762
TPSA (Topological Polar Surface Area)
34.03
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
6
Heavy Atoms
32
Complexity
1263.5197
Exact Mass
454.13266
Monoisotopic Mass
454.13266
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F0545-0366

The XLogP value of 6.74762 indicates that F0545-0366 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.03 Ų, F0545-0366 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0545-0366 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F0545-0366?

The CAS number of F0545-0366 is 681275-85-4.

What is the molecular formula of F0545-0366?

The molecular formula of F0545-0366 is C25H21F3N2OS.

What is the molecular weight of F0545-0366?

The molecular weight of F0545-0366 is 454.13 g/mol.

Where can I buy F0545-0366?

You can request a quote for F0545-0366 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F0545-0366?

Yes, KEHONG BIO provides custom synthesis services for F0545-0366 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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