![(E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one structure](/static/products/680/680600-08-2.png)
(E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one
TL;DR: (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one (CAS 680600-08-2) is a chemical compound with molecular formula C18H11Cl2N3OS and molecular weight 387.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6E)-6-[(3,4-dichlorophenyl)methylidene]-3-(2-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one
Also Known As: (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one, (6E)-6-[(3,4-dichlorophenyl)methylidene]-3-(2-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one
| Molecular Formula | C18H11Cl2N3OS |
|---|---|
| Molecular Weight | 387.00 g/mol |
| LogP | 3.98092 |
| Topological Polar Surface Area | 47.26 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 387.0 |
| Heavy Atoms | 25 |
| Complexity | 1213.0076 |
Chemical Identifiers
| CAS Number | 680600-08-2 |
|---|---|
| SMILES | CC1=CC=CC=C1C2=NN=C3N2C(=O)/C(=C\C4=CC(=C(C=C4)Cl)Cl)/S3 |
Product Overview
(E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one (CAS 680600-08-2), with molecular formula C18H11Cl2N3OS and molecular weight 387.00 g/mol. IUPAC: (6E)-6-[(3,4-dichlorophenyl)methylidene]-3-(2-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one.
Chemical Property Profile of (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one
Property Insights of (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one
The XLogP value of 3.98092 indicates that (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.26 Ų, (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
The CAS number of (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one is 680600-08-2.
What is the molecular formula of (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
The molecular formula of (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one is C18H11Cl2N3OS.
What is the molecular weight of (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
The molecular weight of (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one is 387.00 g/mol.
Where can I buy (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
You can request a quote for (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-6-(3,4-dichlorobenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.