2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide
TL;DR: 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide (CAS 680217-82-7) is a chemical compound with molecular formula C11H7Cl2FN2OS and molecular weight 303.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,6-dichloro-5-fluoro-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide
Also Known As: 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide, 2,6-Dichloro-5-fluoro-N-(thiophen-2-ylmethyl)nicotinamide, 2,6-dichloro-5-fluoro-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide, 2,6-dichloro-5-fluoro-N-[(thiophen-2-yl)methyl]pyridine-3-carboxamide, 2,6-dichloro-5-fluoro-N-(2-thienylmethyl)pyridine-3-carboxamide
| Molecular Formula | C11H7Cl2FN2OS |
|---|---|
| Molecular Weight | 303.96 g/mol |
| LogP | 3.519 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 303.96402 |
| Heavy Atoms | 18 |
| Complexity | 574.67224 |
Chemical Identifiers
| CAS Number | 680217-82-7 |
|---|---|
| SMILES | C1=CSC(=C1)CNC(=O)C2=CC(=C(N=C2Cl)Cl)F |
Product Overview
2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide (CAS 680217-82-7), with molecular formula C11H7Cl2FN2OS and molecular weight 303.96 g/mol. IUPAC: 2,6-dichloro-5-fluoro-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide.
Chemical Property Profile of 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide
Property Insights of 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide
The XLogP value of 3.519 indicates that 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide?
The CAS number of 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide is 680217-82-7.
What is the molecular formula of 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide?
The molecular formula of 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide is C11H7Cl2FN2OS.
What is the molecular weight of 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide?
The molecular weight of 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide is 303.96 g/mol.
Where can I buy 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide?
You can request a quote for 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 2,6-Dichloro-5-fluoro-N-(thien-2-ylmethyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.