N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide
TL;DR: N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide (CAS 680217-80-5) is a chemical compound with molecular formula C12H6Cl3FN2O and molecular weight 317.95 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,6-dichloro-N-(4-chlorophenyl)-5-fluoropyridine-3-carboxamide
Also Known As: N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide, 2,6-dichloro-N-(4-chlorophenyl)-5-fluoropyridine-3-carboxamide, 2,6-dichloro-N-(4-chlorophenyl)-5-fluoro-pyridine-3-carboxamide, C12H6Cl3FN2O
| Molecular Formula | C12H6Cl3FN2O |
|---|---|
| Molecular Weight | 317.95 g/mol |
| LogP | 4.4332 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 317.95297 |
| Heavy Atoms | 19 |
| Complexity | 631.61676 |
Chemical Identifiers
| CAS Number | 680217-80-5 |
|---|---|
| SMILES | C1=CC(=CC=C1NC(=O)C2=CC(=C(N=C2Cl)Cl)F)Cl |
Product Overview
N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide (CAS 680217-80-5), with molecular formula C12H6Cl3FN2O and molecular weight 317.95 g/mol. IUPAC: 2,6-dichloro-N-(4-chlorophenyl)-5-fluoropyridine-3-carboxamide.
Chemical Property Profile of N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide
Property Insights of N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide
The XLogP value of 4.4332 indicates that N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide?
The CAS number of N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide is 680217-80-5.
What is the molecular formula of N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide?
The molecular formula of N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide is C12H6Cl3FN2O.
What is the molecular weight of N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide?
The molecular weight of N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide is 317.95 g/mol.
Where can I buy N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide?
You can request a quote for N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-Chlorophenyl)-2,6-dichloro-5-fluoronicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.