六甲基磷酰胺
TL;DR: 六甲基磷酰胺 (CAS 680-31-9) is a chemical compound with molecular formula C6H18N3OP and molecular weight 179.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
六甲基磷酰胺
N-[bis(dimethylamino)phosphoryl]-N-methylmethanamine
Also Known As: HEXAMETHYLPHOSPHORAMIDE, Hexametapol, HMPA, Hempa, Hexamethylphosphoric triamide
| Molecular Formula | C6H18N3OP |
|---|---|
| Molecular Weight | 179.12 g/mol |
| LogP | 0.3 |
| Topological Polar Surface Area | 26.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 179.11874 |
| Heavy Atoms | 11 |
| Complexity | 139.0 |
| Melting Point | 41 to 7.2 °C |
| Boiling Point | 232.8 °C at 760 mmHg |
| Density | 1.024 at 25.0 °C |
| Solubility | greater than or equal to 100 mg/mL at 64 °F (NTP, 1992) |
| Flash Point | 105.6 °C |
| Vapor Pressure | 0.07 mmHg at 25.0 °C |
| Refractive Index | 1.4572 @ 21 °C |
Chemical Identifiers
| CAS Number | 680-31-9 |
|---|---|
| SMILES | CN(C)P(=O)(N(C)C)N(C)C |
| InChIKey | GNOIPBMMFNIUFM-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 22 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
六甲基磷酰胺 (CAS 680-31-9), with molecular formula C6H18N3OP and molecular weight 179.12 g/mol. IUPAC: N-[bis(dimethylamino)phosphoryl]-N-methylmethanamine.
Chemical Property Profile of 六甲基磷酰胺
Property Insights of 六甲基磷酰胺
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 六甲基磷酰胺. With a topological polar surface area (TPSA) of 26.8 Ų, 六甲基磷酰胺 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 六甲基磷酰胺 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 六甲基磷酰胺?
The CAS number of 六甲基磷酰胺 is 680-31-9.
What is the molecular formula of 六甲基磷酰胺?
The molecular formula of 六甲基磷酰胺 is C6H18N3OP.
What is the molecular weight of 六甲基磷酰胺?
The molecular weight of 六甲基磷酰胺 is 179.12 g/mol.
Where can I buy 六甲基磷酰胺?
You can request a quote for 六甲基磷酰胺 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 六甲基磷酰胺?
Yes, KEHONG BIO provides custom synthesis services for 六甲基磷酰胺 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.