LJ 1144
TL;DR: LJ 1144 (CAS 67931-84-4) is a chemical compound with molecular formula C18H24BrF3N2O and molecular weight 420.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methyl]cyclohexan-1-one;hydrobromide
Also Known As: LJ 1144, 2-(4-(m-Trifluoromethylphenyl)piperazino)methyl-cyclohexanone hydrobromide, 2-((4-(3-(Trifluoromethyl)phenyl)-1-piperazinyl)methyl)cyclohexanone monohydrobromide, Cyclohexanone, 2-((4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)methyl)-, monohydrobromide, 2-[[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methyl]cyclohexan-1-one hydrobromide
| Molecular Formula | C18H24BrF3N2O |
|---|---|
| Molecular Weight | 420.10 g/mol |
| LogP | 4.1646 |
| Topological Polar Surface Area | 23.55 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 420.10242 |
| Heavy Atoms | 25 |
| Complexity | 585.9291 |
Chemical Identifiers
| CAS Number | 67931-84-4 |
|---|---|
| SMILES | C1CCC(=O)C(C1)CN2CCN(CC2)C3=CC=CC(=C3)C(F)(F)F.Br |
Product Overview
LJ 1144 (CAS 67931-84-4), with molecular formula C18H24BrF3N2O and molecular weight 420.10 g/mol. IUPAC: 2-[[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methyl]cyclohexan-1-one;hydrobromide.
Chemical Property Profile of LJ 1144
Property Insights of LJ 1144
The XLogP value of 4.1646 indicates that LJ 1144 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.55 Ų, LJ 1144 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, LJ 1144 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of LJ 1144?
The CAS number of LJ 1144 is 67931-84-4.
What is the molecular formula of LJ 1144?
The molecular formula of LJ 1144 is C18H24BrF3N2O.
What is the molecular weight of LJ 1144?
The molecular weight of LJ 1144 is 420.10 g/mol.
Where can I buy LJ 1144?
You can request a quote for LJ 1144 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for LJ 1144?
Yes, KEHONG BIO provides custom synthesis services for LJ 1144 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.