apramycin
TL;DR: apramycin (CAS 67922-26-3) is a chemical compound with molecular formula C21H41N5O11 and molecular weight 539.28 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,3R,4S,5S,6S)-2-[[(2R,3S,4R,4aR,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol
Also Known As: apramycin, Ambylan, Apralan, Nebramycin II, Nebramycin factor 2
| Molecular Formula | C21H41N5O11 |
|---|---|
| Molecular Weight | 539.28 g/mol |
| LogP | -7.0 |
| Topological Polar Surface Area | 284.0 Ų |
| Hydrogen Bond Donors | 11 |
| Hydrogen Bond Acceptors | 16 |
| Rotatable Bonds | 6 |
| Exact Mass | 539.2803 |
| Heavy Atoms | 37 |
| Complexity | 760.0 |
Chemical Identifiers
| CAS Number | 67922-26-3 |
|---|---|
| SMILES | CN[C@H]1[C@H]([C@@H]2[C@H](C[C@H](C(O2)O[C@@H]3[C@H](C[C@H]([C@@H]([C@H]3O)O)N)N)N)O[C@@H]1O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)N)O)O)O |
| InChIKey | XZNUGFQTQHRASN-XZEBHBPDSA-N |
Product Overview
apramycin (CAS 67922-26-3), with molecular formula C21H41N5O11 and molecular weight 539.28 g/mol. IUPAC: (2R,3R,4S,5S,6S)-2-[[(2R,3S,4R,4aR,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol.
Chemical Property Profile of apramycin
Property Insights of apramycin
The XLogP value of -7.0 indicates that apramycin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 284.0 Ų indicates high polarity, suggesting apramycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, apramycin has 11 hydrogen bond donor(s) and 16 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of apramycin?
The CAS number of apramycin is 67922-26-3.
What is the molecular formula of apramycin?
The molecular formula of apramycin is C21H41N5O11.
What is the molecular weight of apramycin?
The molecular weight of apramycin is 539.28 g/mol.
Where can I buy apramycin?
You can request a quote for apramycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for apramycin?
Yes, KEHONG BIO provides custom synthesis services for apramycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.